Tuesday, December 31, 2019

Effective Leadership Characteristics And Principles

Personally, in an effort to enhance professional leadership skills, there are many opportunities for growth. Diversity training would provide more insight into understanding the importance of developing relationships with everyone in a diverse group. Building these relationships and understanding everyone presents the opportunity to unite everyone and make them become more invested and align them with the vision and goals of the organization. There are many examples of effective leadership characteristics and principles, it is the job of the leader to adapt different skills to fit their team and goals. Another skill to focus on for personal growth and enhancement would be the ability to encourage employees to become self-sufficient and†¦show more content†¦More importantly this theory reinforces the thought of being flexible and accommodating when necessary. A leader that believes there is one outlook and leadership type will miss many growth and professional development opportunities. Some effective key concepts to coach/mentor and develop others include will be similar to the requirements for effective leadership. A coach/mentor can also be external which limits their accessibility on a daily basis to the organization and it issues. A coach or mentor must be extremely observant when they interact with teams and organizations so that they have an accurate understanding of the situation (McCarthy, 2014). The coach must be ultimately focused on helping the team or organization overcome an obstacle or meet goals. A coach or mentor can also be an employee that is not in a leadership position. The opportunity to coach or mentor someone can be simply based on a higher knowledge of an area than others. According to McCarthy (2014) there are two approaches to mentoring developmental mentoring as well as sponsorship mentoring. Developmental mentoring is focused on helping others, in groups on individually, expand their way of thinking and better be able to guide themselves. The developmental mentoring theory helps the mentee to become more aware and self-sufficient and grow overall. The sponsorship approach focuses more on helping the mentees find success within their

Monday, December 23, 2019

Human Perception And The Evolution Of Intelligence

The air nipped at my body while ascending the enormous mountain, tired I yearned for a break from this steep mountain side but, the break did not come till the mountain top was reached. I looked around the high peak and embraced the vast wilderness that surrounded it. A sea of green trees overwhelmed my senses, the bright blue sky pierced the tree line which ascended into the heavens. The beautiful scenery made me think long and hard about why all of this exists the mountains, trees and even myself. The deeper I went, the more confused and lost I seemed to be, and no end seemed to be in sight for this confused feeling I felt towards self-awareness The questions of sentient perception have plagued man since the dawn of his very own†¦show more content†¦Dualism is a huge concept in the theory of consciousness and it states the perception of one self falls outside of the known physical realm; â€Å"Substance dualism, such as traditional Cartesian dualism (Descartes 1644), asse rts the existence of both physical and non-physical substances. Such theories entail the existence of non-physical minds or selves as entities in which consciousness inheres. Though substance dualism is at present largely out of favor, it does have some contemporary proponents (Swinburne 1986, Foster 1989, 1996). â€Å"(Stanford) This is a theory that falls under dualism as it explains perception as something that is not physical. According to this theory perception is something that is within us, both physical and nonphysical elements exist within The Cartesian System is a theory about consciousness deeply rooted in the belief of a god. â€Å"The essence of mind is self-conscious thinking; the essence of matter is extension in three dimensions. God is a third, infinite substance, whose essence is necessary existence. God unites minds with bodies to create a fourth, compound substance, human beings. Humans obtain general knowledge by contemplating innate ideas of mind, matter, and God†(britannica) In the Cartesian system god is essential. God is the one who unites the mind with the body to create self-awareness. If god was not present

Sunday, December 15, 2019

Nav1.7 is a sodium ion channel that in humans is encoded by the SCN9A gene Free Essays

Introduction Literature Nav1.7 is a sodium ion channel that in humans is encoded by the SCN9A gene(Stewart et al, 2003). It is highly expressed in pain sensing neurons which are of two types, the nociceptive dorsal root ganglion (DRG) neurons and sympathetic ganglion neurons, which are parts of the autonomic (involuntary) nervous system (Cox et al, 2006). We will write a custom essay sample on Nav1.7 is a sodium ion channel that in humans is encoded by the SCN9A gene or any similar topic only for you Order Now In human’s mutation in SCN9A cause three human pain disorders, resulting in bi-allelic loss of function mutations in Channelopathy-associated insensitivity to pain (CIP), while activating mutations causes temporal pain in Paroxysmal External Pain Disorder (PEPD) and primary Erythermalgia (PE) (Drenth et al, 2007). Mutations in SCN9A leads to a complete inability to experience pain, which is due to lack of protein production. In organisms such as mammals amphibians and reptiles, it is of upmost significances to have the intelligence to feel harmful situations (Shevelkin et al, 2005). Pain which is a sense protects us from damage of the tissue by notifying us of situations that are able to cause injuries and stimulate tissue recovery. Combining investigation of Nav1.7 Variation with Pain Cohorts The increased activity of Nav1.7 due to SCN9A mutations are due to very serious pain connected to paroxysmal extreme pain disorder and primary erythermalgia which has clearly noticeable association of several clinically recognizable features (Estacion et al. 2009). In this research they investigated 578 individuals who shared similar characteristics with osteoarthritis (OA), five showed an important relationship with pain score in a linear relapse which include a modification in age, sex, body mass index and age-gender interaction; rs6432896, P = 0.048; rs7604448, P = 0.036; rs10930214,P = 0.027; rs6746030, P= 0.016; and rs7595255, P = 0.02, after 27 SNPs were been screened in SCN9A. Out of the five single nucleotide polymorphisms that showed an important association with pain, the last four were in a bond or union that lacked stability, after the disequilibrium bond analysis. Four of the SNPs which have important affiliation with pain score are all located in the introns and did not influence mRNA order. Cepeda et al (2007) state that SNP rs6746030 with little frequency encodes a tryptophan (Nav1.7-1150W), while a higher frequency encodes for arginine (Nav1.7-1150R) and is found on exon 18 and it influences the amino acid at point 1150 of Nav1.7, in other words, 1150R is a preserved amino acid and can be added to the normal action or work of Nav1.7. It is evident that an individual in the general public having rs6746030 A allele would be assumed to feel pain provocation when compared to others. The limitations of this research are in the modification of their age, gender, body mass index (BMI), and also the examination of individuals with similar characteristics (cohorts).Further research and examination could be carried out on SNP rs6746030 for analysis with additional pain cohorts and also with individuals having different characteristics because of its active result in regression examination. Clinical analysis of rs6746030 Diatchenko et al (2005) point out that pain reaction to various investigative processes was examined. The result was achieved that C-fiber activation was actively combined with rs6746030. The result suggests that A-allele-driven clinical pain is mediated by the arousal or stimulation of C-fiber which indicates the feeling of diffuse, dull, aching pain. Diatchenko et al. (2007) further claim that individual having the genotype AA feels more pain while individual having GG genotype feels less pain because clinical and investigative pain analysis backs an additive idea for the result of rs6746030 alleles. Similarly, Waxman et al. (2005) point out that SCN9A is a consequential contributor to human pain sensation and clinical pain ailments and this is as a result of the stimulation of mutation in SCN9A which leads to an acute irregular pain while an unstimulated mutation results in a total absence of pain. Diatchenko et al. (2005) feel that pharmacological materials that alter the respo nsibility of SCN9A(Nav1.7) are possibly beneficial in the treatment of this condition. Individual suffering from distinct amount of pain for each stimulus is due to their rs6746030 genotype. As each individual seems to have distinct genetic susceptiveness to pain, further analysis should be carried out to be conscious of the fact that openness to various class of anaesthetic is also genetically determined. References Cepeda M.S, Camargo F, Zea C, Valencia L.(2007). Tramadol for osteoarthritis: A systematic review and metaanalysis. 34:543–555. Cox j.j, Reimann F, Nicholas A. K, Thornton G, Roberts E, Springell K, Karbani G, Jafri H, Mannan J, Raashid Y, Al-Gazali L, Hamamy H, Valente E.M, Gorman S, Williams R, McHale D.P, Wood J.N, Gribble F.M, Woods C.G.(2006). An SCN9A channelopathy causes congenital inability to experience pain. Nature. 444:894–8. Diatchenko L, Nackley A.G, Tchivileva I.E, Shabalina S.A, Maixner W.(2007). Genetic architecture of human pain perception. Trends Genet. 23:605–613. Drenth J.P, Waxman S.G.(2007). Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders. J Clin Invest. 117:3603–9. Estacion M, et al.(2007). A sodium channel gene SCN9A polymorphism that increases nociceptor excitability. Ann Neurol. 66:862–866. Shevelkin A.V, Kozyrev S.A, Nikitin V.P, Sherstnev V.V.(2005). In vivo investigation of genome activity and synaptic plasticity of neurons in snails during learning. Neurosci Behav Physiol. 35:595–603. Stewart W.F, Ricci J.A, Chee E, Morganstein D, Lipton R.(2003). Lost productive time and cost due to common pain conditions in the US workforce. Jama. 290:2443–54. Waxman S.G, Dib-Hajj S.(2005). Erythermalgia: Molecular basis for an inherited pain syndrome. Trends Mol Med. 11:555–562. 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Saturday, December 7, 2019

The revenge of islam Essay Example For Students

The revenge of islam Essay HOUSTON, Texas (CNN) Enron security guards were stationed on the 19th and 20th floors of the companys building here Tuesday to prevent further shredding of documents, company lawyers said during a federal court hearing. Former executive Maureen Castaneda said Monday employees were shredding documents as late as January 14, in spite of the companys December bankruptcy filing that costs thousands of investors and employees their life savings. In the wake of the reports of continued shredding, Enron lawyers said the company allowed FBI agents in the building to interview employees and that guards had been posted round the clock to prevent more document destruction. Some 40 attorneys representing investors asked a judge to place federal marshals or an outside firms security guards in the Enron building to prevent shredding. The lawyers also asked the judge to take possession of all documents relevant to the investigation into the collapse of the energy giant including boxes of shredded papers they said company executives ordered destroyed. It was also revealed in court that shredded documents were found in a wastebasket, which was turned over to authorities. It is not clear who conducted the search in which the papers were discovered. Packing materials become evidenceMORE STORIES Shredding through history Ex-Enron exec: Shredding went on after probe began VIDEO/AUDIO Enron collapse hurts Houston charities Enron: A tale of two meetings MORE STORIES Ex-Enron exec: Shredding went on after probe began Lawyer who wrote document memo quizzed Terms set for sale of Enrons Indian plant Andersen blame game heats up EXTRA INFORMATION Guide to the fall of Enron Bush administration ties Chapter 11 timeline RESOURCES In-Depth: The end of Enron? Protect your 401(k) TIME.com: Inside the scandal In Focus: What happened? LEGAL RESOURCES Latest Legal News Law Library FindLaw Consumer Center Select a topicBankruptcyDiscriminationDivorceEstate PlanningLandlord-TenantPersonal InjuryTa xes Castaneda said she took boxes of shredded paper home with her to use as packing material. She later realized the significance of the refuse. She recalled e-mails telling employees how to handle financial documents. One said our policy is not to destroy documents, given the threatening legal suits, she told CNN. And thats what made me realize that I had more than just shreds. It is an absolute smoking gun, said Castanedas attorney, Paul Howes, referring to the shredded papers. Howes is with Milberg, Weiss, a San Diego-based firm that specializes in class action suits. The firm also represents Amalgamated Bank, which lost about $17 million in the Enron collapse, and the regents of the California University System, which lost $144 million. Castaneda told CNN on Tuesday that her former employer had become arrogant. There was a lot of arrogance at the company to the point where you think you can lie to Wall Street and get away with it, Castaneda said. You cant get more arrogant than that. Enron spokesman Mark Palmer told CNN the company told its employees in a company-wide e-mail October 25 to retain all documents which include handwritten notes, recordings, e-mails and any other method of information recording. You should know that this document preservation requirement is a requirement of federal law, and you could be individually liable for civil and criminal penalties if you fail to follow these instructions, the e-mail said. Palmer said the company sent out four e-mails on the subject the most recent one last week. Each one broadened the scope of what employees are asked to retain, he said. Howes senior partner William Lerach said some of the shreds Castaneda took home contained references to phony partnerships set up to inflate the profits. He called the reported document shredding a horrible, horrible decision and said the documents would be pieced back together. Its always better to live with whatever the facts are, however bad they are, than destroy the evidence, Lerach said. House committee subpoenas comingKen Johnson, spokesman for the Republicans on the House Energy and Commerce Committee, said in a statement the allegations were likely to be of interest to our committee as well as the Justice Department. Making bad business decisions is one thing, but hiding or covering up bad decisions is another, Johnson said. If it turns out it is true that they were shredding documents while knowing inquiries were under way by Congress and the Department of Justice somebodys probably going to be in hot water. The House committee will issue subpoenas to executives of Arthur Andersen, the accounting firm that once handled the energy companys finances. According to committee sources, among those expected to be subpoenaed to appear at a hearing Thursday is David Duncan, a former Andersen partner who had been in charge of the Enron audit. If Duncan is subpoenaed, Johnson said, he probably would exercise his right to protection against self -incrimination under the Fifth Amendment of the U.S. Constitution. Duncan was fired after reports that he ordered the destruction of Enron documents. He said through his attorney that he was following the advice of in-house counsel. Joseph Berardino, Andersens CEO, will also be subpoenaed, sources said, noting that both men indicated through their attorneys that they would not appear voluntarily. Nancy Temple, an Arthur Andersen attorney, and Michael Odom, a risk management partner, were described by one source as not reluctant witnesses. But they too will be subpoenaed because otherwise some of the information they have about Andersen could be considered privileged, the source said. CNN Correspondent Ed Lavandera and CNN Capitol Hill Producer Ted Barrett contributed to this report. .u8bafd72b69e35bffdedb2c2adf141a56 , .u8bafd72b69e35bffdedb2c2adf141a56 .postImageUrl , .u8bafd72b69e35bffdedb2c2adf141a56 .centered-text-area { min-height: 80px; position: relative; } .u8bafd72b69e35bffdedb2c2adf141a56 , .u8bafd72b69e35bffdedb2c2adf141a56:hover , .u8bafd72b69e35bffdedb2c2adf141a56:visited , .u8bafd72b69e35bffdedb2c2adf141a56:active { border:0!important; } .u8bafd72b69e35bffdedb2c2adf141a56 .clearfix:after { content: ""; display: table; clear: both; } .u8bafd72b69e35bffdedb2c2adf141a56 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u8bafd72b69e35bffdedb2c2adf141a56:active , .u8bafd72b69e35bffdedb2c2adf141a56:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u8bafd72b69e35bffdedb2c2adf141a56 .centered-text-area { width: 100%; position: relative ; } .u8bafd72b69e35bffdedb2c2adf141a56 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u8bafd72b69e35bffdedb2c2adf141a56 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u8bafd72b69e35bffdedb2c2adf141a56 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u8bafd72b69e35bffdedb2c2adf141a56:hover .ctaButton { background-color: #34495E!important; } .u8bafd72b69e35bffdedb2c2adf141a56 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u8bafd72b69e35bffdedb2c2adf141a56 .u8bafd72b69e35bffdedb2c2adf141a56-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u8bafd72b69e35bffdedb2c2adf141a56:after { content: ""; display: block; clear: both; } READ: How did pop art challenge beleifs in consumerism Essay